Model 3500

16-Channel Extracellular Differential Amplifier (A-M Systems)


16 low noise, high-gain, full-featured extracellular amplifier channels, designed for amplifying microvolt-level input signals.

Low Noise:   1 µV p-p

Flexible:    Touch Screen and Computer Control

Integrated:   MATLAB, LabVIEW Drivers

The Model 3500 features 16 independent channels, or amplifiers, a front panel touch screen, computer control capabilities and a built-in calibrator.

Users can also easily monitor the activity on any two channels via the convenient front panel BNC signal monitors.

Multiple instruments and multiple channels can be controlled from a single computer program.

The Model 3500 offers:

  • 13 gain settings from ×2 to ×20,000
  • 8 high-pass filter settings from 0.3 Hz to 500 Hz
  • 8 low-pass filter settings from 100 Hz to 20.0 kHz
  • TTL Control of instrument mode
  • Twin stimulation busses to pass current
  • Channel Monitors
  • Built-In Calibration signal
  • Common Reference Bus
  • Blanking
  • PC control capability
  • MATLAB® and LabVIEW SDK and drivers available
  • 3U rackmount enclosure accommodates all 16 channels

Model 3500 Control Software

The Model 3500 is supplied with optional Windows control software. This software controls all features of the amplifier via a USB port (cable included).

The program also enables the storage of an unlimited number of 16-Channel parameter files, as well as provides a real-time notepad that logs changes in parameter settings or experimenter-added notations.

Windows Control Software Screenshot for Model 3500

The Model 3500 includes:

  • USB Cable: Type A to Type B
  • 16 40-inch input cables
  • Control software
  • Operator's manual
  • Rack mount hardware
  • Power supply



Voltage, fB = 10 Hz-10 kHz, typical: 1.0 µV, p-p
Offset Voltage
Average Drift, typical: ±4.0 µV/°C
Average Drift, maximum: ±30.0 µV/°C
Bias Current
Initial Bias Current, maximum: ±0.4 nA
Offset Current
Input Offset Current, maximum: ±0.4 nA
Input Impedance
1012 Ω || 4 pF
Inter-channel Crosstalk
100 dB at 1 kHz
Input Voltage Size
VDC: 1 V
VAC: Gain / 10 V
Common Mode Rejection (CMR): 100 dB
Rated Output
Voltage Output: ±11 V
Output Resistance: >100 Ω
Low Cut-Off Filter
Cut-Off Frequencies: 0.3, 1.0, 3.0, 10.0, 30.0, 100, 300, 500 Hz
Cut-Off Rate: 40dB/decade
High Cut-Off Filter
Cut-Off Frequencies: 0.1, 0.3, 0.5, 1.0, 3.0, 5.0, 10.0, 20.0 kHz
Cut-Off Rate: 40 B/decade
Notch Filter
Center Frequency: 50 Hz or 60 Hz
Rejection: >35 dB
13 values from ×2 to ×20,000